... of 21 -OH 0 CH 18-glucuromde 18-Qlucuronn capable of degrading aldosterone completely to a biologically inactive form (Chart et al. 1956). These biotransformations are very rapid, 95-100 per cent of aldosterone being removed from the blood in one circuit through the liver. ... transformations of the molecule rather than being oxidised as occurs in other 1 10-hydroxylated steroids (Kohler et al. 1964).
|Title||:||Aldosterone and aldosteronism|
|Author||:||Eric John Ross|
|Publisher||:||Lloyd-Luke (Medical Books) Ltd - 1975|