Base Excision Repair of DNA Damage

Base Excision Repair of DNA Damage

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Reviews the latest research in the field for researchers and clinicians. After a general introduction to DNA base excision repair, chapters cover uracil DNA glycosylases, repair of oxidized purines in DNA, mammalian mismatch-specific DNA glycosylases, repair of apurinic/apyrimidic sites in DNA by AP endonucleases, mutagenesis of abasic sites, a proCalf 5a#39; to 3a#39; exo/endonuclease must slide from a 5a#39; end of the substrate to perform structure-specific cleavage. ... deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene. l Bacteriol 1995; 177(2):364-371.

Title:Base Excision Repair of DNA Damage
Author:Ian D. Hickson
Publisher:Springer Science & Business Media - 1997-01-01


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