G Protein Signaling

G Protein Signaling

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Alan V. Smrcka presents a collection of cutting-edge methods for investigating G protein signaling from a variety of perspectives ranging from in vitro biochemistry to whole animal studies. Among the readily reproducible techniques presented are those for the purification of G proteins and effectors enzymes, assays of these purified G proteins and effector enzymes, and for the study of G proteins interactions with effectors in intact cells. Additional methods are provided for assaying G protein coupled receptor structure, function, and localization, and for studying the physiological roles for endogenous G proteins.... 1310a€“1317. 4. Srinivasa, S. P., Bernstein, L. A., Blumer, K. J., and Linder, M. E. (1998) Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae. ... Chem. 274, 38, 260a€“38, 267. 7. Druey, K. M., Ugar, O., Caron, J. M., Chen, C.-K., Backlund, P. S., and Jones, T. L. Z. (1999) ... (1988) Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Plainview, NY.

Title:G Protein Signaling
Author:Alan V. Smrcka
Publisher:Springer Science & Business Media - 2004-01


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