Expert researchers critically review and evaluate the most common and important neurotoxins used today in neuroscience research. Each informative chapter thoroughly describes the significant mechanisms of action of a neurotoxin, as well as fully discussing the limits on their use and their clinical applicability. Several clinically oriented chapters are significant for neurologists treating Parkinsonism, for psychiatrists treating drug abuse and neurodegenerative disorders, and for primary care physicians treating patients with appetite suppressants. Highly Selective Neurotoxins provides all the basic knowledge needed to obtain a predictable experimental outcome with these neurotoxins.The benefits of long-term pharmacotherapy with PHEN/FEN on weight loss must be carefully considered against the drug-engendered health risks. ... be explained by the principles of interspecies scaling (131, 132), which dictate that in order to calculate a comparable dose of drug in different species, ... The surface areas of a 400-g rat and a 90-kg human are approx 0.054 and 2.0 m2, respectively (134).
|Title||:||Highly Selective Neurotoxins|
|Publisher||:||Springer Science & Business Media - 1997-10-30|