LPS-stimulated cytokine production may be inhibited by the release of TGF-B1 or prostaglandin E2, and play a crucial role in the onset of ... A LPS-LBP complex then induces signaling in a target cell by binding to two receptors, CD 14 and toll- like receptor 4 (TLR4). ... In alcoholic liver injury, hepatic macrophages (Kuplfer cells) constitute the main target cell for LPS and activation of the cells by LPS isanbsp;...
|Title||:||Liver: A Complete Book on Hepato-Pancreato-Biliary Diseases|
|Publisher||:||Elsevier India - 2009-01-01|