Microarray Image Analysis

Microarray Image Analysis

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To harness the high-throughput potential of DNA microarray technology, it is crucial that the analysis stages of the process are decoupled from the requirements of operator assistance. Microarray Image Analysis: An Algorithmic Approach presents an automatic system for microarray image processing to make this decoupling a reality. The proposed system integrates and extends traditional analytical-based methods and custom-designed novel algorithms. The book first explores a new technique that takes advantage of a multiview approach to image analysis and addresses the challenges of applying powerful traditional techniques, such as clustering, to full-scale microarray experiments. It then presents an effective feature identification approach, an innovative technique that renders highly detailed surface models, a new approach to subgrid detection, a novel technique for the background removal process, and a useful technique for removing qnoise.q The authors also develop an expectationa€“maximization (EM) algorithm for modeling gene regulatory networks from gene expression time series data. The final chapter describes the overall benefits of these techniques in the biological and computer sciences and reviews future research topics. This book systematically brings together the fields of image processing, data analysis, and molecular biology to advance the state of the art in this important area. Although the text focuses on improving the processes involved in the analysis of microarray image data, the methods discussed can be applied to a broad range of medical and computer vision analysis areas.A Accumulator array center, 280 Adaptive shape techniques, 5 Adaptive snake shape techniques, 37 A/D converter, see Analogue to digital ... 12, 15 fuzzy c- means algorithm pseudo-code, 273 generalized Hough transform algorithm pseudo-code, 280 gene regulatory ... 174 master block identification pseudo- code, 103 mean filter pseudo-code, 104 median filter pseudo-code, 104 PCC pseudo-code, anbsp;...

Title:Microarray Image Analysis
Author:Karl Fraser, Zidong Wang, Xiaohui Liu
Publisher:CRC Press - 2010-01-25


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