The genomics revolution would not have been possible without the 'parallelisation' offered by microarray technology. This technological - and commercial - success has since been emulated by other applications areas, with a tremendous amplification of innovation. This book describes the fundamentals and latest developments in microarray technology, as well as its future directions. It presents detailed overviews of the different techniques of fabricating microarrays, of the chemistries and preparative steps involved, of the different types of microarrays, and of the instrumentation and optical issues involved.It is expected, that systems will soon become available that will automatically scan TMA slides and measure the intensity of staining for each individual TMA spot. In one of our studies we compared manual versus automated analysis of p21anbsp;...
|Title||:||Microarray Technology and Its Applications|
|Author||:||Uwe R. Müller, Dan V. Nicolau|
|Publisher||:||Springer Science & Business Media - 2005|