As a major defence against environmental damage to cells DNA repair is present in all organisms including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. DNA repair is involved in processes that minimise cell killing, mutations, replication errors, persistence of DNA damage and genomic instability. Abnormalities in these processes have been implicated in cancer and ageing. This book presents leading-edge research from around the world in this frontal field.The RAD51 Homology-Directed HR-Repair Pathway Compared to NHEJ, the details of HR-repair are fairly poorly ... and this modification is required for efficient nuclear DSB repair- focus formation (Kitao and Yuan 2002, Yuan et al 2003).
|Title||:||New Research on DNA Repair|
|Author||:||Breehn R. Landseer|
|Publisher||:||Nova Publishers - 2007|