Novel Technologies for Vaccine Development

Novel Technologies for Vaccine Development

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This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a a€œmust reada€ for all those involved in vaccine development, both in academia and industrial vaccine development.... 54-eng.php; bfaxarchive/ bf15dec09.pdf; ... However, most of these mutations reduce virus growth in cultured cells and/or eggs and may thus not allow efficient vaccine production. ... A lab-adapted human influenza A virus (A/WSN/33, H1N1; WSN) with mutations in the nuclear localization signal of M1 replicated comparably to wild-type virus inanbsp;...

Title:Novel Technologies for Vaccine Development
Author:Igor Lukashevich, Haval Shirwan
Publisher:Springer - 2014-11-13


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