This volume is intended for neuropharmacologists, psychopharmacologists, pharmacologists, pharmacists, sleep researchers, translational neuroscience researchers, and other basic researchers and clinical scientists interested in an interdisciplinary approach to sleep medicine. The level of the book is aiming at CNS researchers, drug development scientists, basic and clinical sleep researchers, as well as senior medical students and fellows in psychiatry and neurology. Orexin and Sleep provides a unique resource, giving a comprehensive and highly readable summary of the basic concepts in orexin biology and pharmacology along with clinical applications in sleep medicine in general, and narcolepsy in particular.... Sakurai T (2010) Histamine-1 receptor is not required as a downstream effector of orexin-2 receptor in maintenance of basal sleep/wake states. ... Hwang LL, Chen CT, Dun NJ (2001) Mechanisms of orexin-induced depolarizations in rat dorsal motor nucleus of vagus neurones in vitro. ... arousal system neurons and drives an intrinsic Ca2+-dependent resonance in LDT and PPT cholinergic neurons.
|Title||:||Orexin and Sleep|
|Author||:||Takeshi Sakurai, S.R. Pandi-Perumal, Jaime M. Monti|
|Publisher||:||Springer - 2015-10-19|