Introduces a range of data analysis problems encountered in drug development and illustrates them using case studies from actual pre-clinical experiments and clinical studies. Includes a discussion of methodological issues, practical advice from subject matter experts, and review of relevant regulatory guidelines.A Practical Guide Alex Dmitrienko, Christy Chuang-Stein, Ralph B. Da#39;Agostino ... narrow, an unweighted linear model may suffice, while a larger range may require a more advanced and weighted model. ... replicates are often not independent for many analytical procedures because of the steps followed in preparation andanbsp;...
|Title||:||Pharmaceutical Statistics Using SAS|
|Author||:||Alex Dmitrienko, Christy Chuang-Stein, Ralph B. D'Agostino|
|Publisher||:||SAS Institute - 2007-02|