Proteolysis in Cell Functions

Proteolysis in Cell Functions

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The proteolytic enzymes have an essential function in all cells. Their activities are regulated by the rate of synthesis, activation of proenzymes and by the rate of synthesis of their inhibitors. They are synthesized in ribosomes like any other proteins and transported to various storage organelles or secreted from the cells and are activated in the pericellular space or in interstitium. Various cells and tissues have their characteristic enzyme patterns which serve their specific functions. Proteolytic enzymes take part and often have a regulatory role in numerous phases of cell function, e.g. cell division, migration, apoptotic as well as necrotic cell death etc. Diseases in which proteolysis has been subject of active research are e.g. cancer metastasis, viral infections, e.g. HIV, and Alzheimer's disease. They are also an essential part in any tissue remodelling, wound healing, throughout the kingdom of fauna and flora.(Eds.) 1OS Press, 1997 Conformation of the DE-loop is Crucial for Proteolytic Degradation of Photosystem n Reaction Centre ... of all thylakoid proteins due to light-induced selective damage to Dl and subsequent stoichiometric replacement of it. ... PSII of plants and cyanobacteria is embedded in the photosynthetic thylakoid membrane, where it functions as a water-plastoquinone-oxido- reductase.

Title:Proteolysis in Cell Functions
Author:Väinö K. Hopsu-Havu, Mikko Järvinen, Heidrun Kirschke
Publisher:IOS Press - 1997-01-01


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