Presents an up-to-date treatment of research strategies, clinical and commercial developments, and regulatory and economic issues pertaining to the formulation of effective and safe red blood cell substitutes. The text examines regulatory and socioeconomic aspects of blood substitute products, and global tranfusion practices from the perspective of blood banks and the US Food and Drug Administrations. It also includes the mechanisms of action and consequences of blood substitute administration.B. This diagram shows physical penetration of the endothelial layer by unmodified (dimeric) hemoglobin. The hemoglobin binds NO before it is able to reach the vascular smooth muscle layer, with resultant vasoconstriction. C. This diagramanbsp;...
|Title||:||Red Blood Cell Substitutes|
|Publisher||:||CRC Press - 1997-09-05|