Weighted Network Analysis

Weighted Network Analysis

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High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a variety of biological systems, bridging the gap from individual genes to biologically or clinically important emergent phenotypes. Manual SNP Selection NEO provides great flexibility to the user on how to anchor traits to markers. ... We recommend that conservative measures of genome-wide QTL significance (Lander and Kruglyak 1995) and false discovery rate be applied when selecting the initial causal anchor(s). ... Automatic SNP Selection NEO can also be used to 11.6 The Network Edge Orienting Method 303.

Title:Weighted Network Analysis
Author:Steve Horvath
Publisher:Springer Science & Business Media - 2011-04-30


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